Isocyanate free polyurethane coatings. Exposure to isocyanates at work can cause asthma. Isocyanates are chemicals used in many products, including polyurethane foams and automotive paint. Inhalation is the most common form of exposure for workers. Isocyanates are compounds containing the isocyanate group (-NCO). Isocyanates can also sensitize workers, making them subject to severe asthma attacks if they are exposed again. They react with compounds containing alcohol (hydroxyl) groups to produce polyurethane polymers, which are components of polyurethane foams, thermoplastic elastomers, spandex fibers, and polyurethane paints. Isocyanates are a powerful irritant to the mucous membranes of the eyes and gastrointestinal and respiratory tracts. . Isocyanates can also enter a worker's body through unprotected skin. Occupational asthma has overtaken asbestosis as the leading cause of new work-related lung disease. Workers who manufacture plastics or apply polyurethane coatings may be at risk of exposure. Isocyanates are powerful irritants to the mucous membranes of the eyes and gastrointestinal and respiratory tracts. Apr 22, 2025 · Isocyanates are reactive chemical compounds containing one or more isocyanate groups (-NCO). They are most commonly used as crosslinkers and curing agents in polyurethane, polyurea, and epoxy formulations. Isocyanates result from chemical reactions in plastics and polyurethanes. In organic chemistry, isocyanate is the functional group with the formula R−N=C=O. Organic compounds that contain an isocyanate group are referred to as isocyanates. Direct skin contact can also cause marked inflammation. In organic chemistry, isocyanate is the functional group with the formula R−N=C=O. pgu ylb znh juj qnw rqw osu isn fuy jjn rfb nih ucs coc vlv